I don't know the full answer to this.
In fact, this is an open area of research.
-Here's a simple proposal (in fact, this is the model used in my [RustBelt work]({{ site.baseurl }}{% post_url 2017-07-08-rustbelt %}), and it is also how [miri](https://github.com/solson/miri/) implements pointers):
+Here's a simple proposal (in fact, this is the model of pointers used in [CompCert](https://hal.inria.fr/hal-00703441/document) and my [RustBelt work]({{ site.baseurl }}{% post_url 2017-07-08-rustbelt %}), and it is also how [miri](https://github.com/solson/miri/) implements pointers):
A pointer is a pair of some kind of ID uniquely identifying the *allocation*, and an *offset* into the allocation.
Adding/subtracting an integer to/from a pointer just acts on the offset, and can thus never leave the allocation.
Subtracting a pointer from another is only allowed when both point to the same allocation (matching [C++](https://timsong-cpp.github.io/cppwp/n4140/expr.add#6)).[^2]